[Omeo33] Art 0868 - Homeopathy, 2008, 97 (4), 185-189

[Dott. Italo Grassi]

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Italo
----- Original Message ----- 
From: "Gino Santini" <g.santini a ismo.it>
To: <omeopatia33 a siomi.it>
Sent: Saturday, November 22, 2008 7:20 PM
Subject: [Omeo33] Art 0868 - Homeopathy, 2008, 97 (4), 185-189


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SIOMI / Redazione di Omeopatia33
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> Lipid peroxidation, erythrocyte antioxidants and plasma antioxidants
> in osteoarthritis before and after homeopathic treatment
> S. Pinto, A.V. Rao and A. Rao
>
> Objective - This study attempts to evaluate the status of oxidative
> stress in osteoarthritis (OA), by measuring some parameters of
> oxidant stress and antioxidant defenses in blood, before and after
> homeopathy treatment, and to asses the role, if any, of homeopathic
> treatment in modulating free radical toxicity in OA.
> Methods - Erythrocyte lipid peroxidation (LP), erythrocyte
> antioxidants viz., glutathione (GSH), glutathione reductase (GR),
> superoxide dismutase (SOD), catalase (CT) and plasma antioxidants
> viz., ceruloplasmin, glutathione-S-transferase (GST), vitamin C,
> total antioxidant activity (AOA) were determined in eighty one
> patients with OA and fifty three normals. Forty seven patients, who
> were treated with homeopathic remedies were considered for the
> follow-up studies.
> Location - Father Muller Homeopathic Hospital, Mangalore, South
> Karnataka, India.
> Results - Erythrocyte LP (0 hour, p < 0.001; 2 hours, p < 0.01; and
> susceptibility to LP, p < 0.05) and SOD (p < 0.05) were significantly
> higher, whereas plasma vitamin C (p < 0.01) and AOA (p < 0.001) were
> significantly lower in OA patients when compared to controls. In
> follow-up patients the erythrocyte LP (0 hour, p < 0.01; 2 hours, p <
> 0.01; and susceptibility to LP, p < 0.01) and SOD (p < 0.01) were
> significantly lower when compared to their pretreatment values.
> Plasma vitamin C attained a normal range. The AOA activity after
> treatment was not significantly different from that observed before
> treatment.
> Conclusion - Oxidative stress increased in OA as indicated by
> increased LP, SOD, decreased vitamin C and AOA. On homeopathic
> treatment the LP has decreased in the erythrocytes which shows and
> reduced oxidative stress. This is further evidenced by returning of
> plasma vitamin C and erythrocyte SOD to the normal levels, but
> oxidant stress has not been completely overcome as plasma AOA
> remained low after treatment.
>
> Disponibile il full-text su richiesta
> -- 
>
> === mailto:g.santini a ismo.it
>


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