[Omeo33] Art 1202 - FACT, 2010, 15 (2), 104-106

[Gino Santini]

Systematic reviews of RCTs in homeopathy A focused appraisal
Robert T Mathie

This overview aims to outline and clarify the different types of  
systematic review that have analysed the clinical research evidence in  
RCTs of homeopathy. In contrast to most discussions on this subject,  
it pays due regard to key characteristics of study design in the  
original RCTs that comprise the systematic reviews. Based on this  
clarified perspective of past research, future investigations can be  
focused more sharply and effectively.
Those who evaluate homeopathy research tend to place greatest emphasis  
on systematic reviews of all medical conditions grouped together  
(comprehensive systematic reviews). However, the worth of such  
contributions – and therefore the relevance of their conclusions – is  
limited by the disparate modalities of homeopathy investigated and by  
the heterogeneous range of medical conditions being examined  
collectively. This brief appraisal highlights systematic reviews in  
which such heterogeneity has been avoided or reduced by focusing on a  
given medical diagnosis or group of related diagnoses. Importantly,  
this approach also recognises that some medical problems may be more  
or less responsive than others to homeopathic intervention.

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