[Omeo33] Art 1189 - Homeopathy, 2011, 100 (1), 95-100
Gino Santini
g.santini a ismo.it
Dom 3 Apr 2011 23:56:08 CEST
Adjunctive homeopathic treatment in patients with severe sepsis: a
randomized, double-blind, placebo-controlled trial in an intensive
care unit
M. Frass, M. Linkesch, S. Banyai, G. Resch, C. Dielacher, T. Löbl, C.
Endler, M. Haidvogl, I. Muchitsch and E. Schuster
Background - Mortality in patients with severe sepsis remains high
despite the development of several therapeutic strategies. The aim of
this randomized, double-blind, placebo-controlled trial was to
evaluate whether homeopathy is able to influence long-term outcome in
critically ill patients suffering from severe sepsis.
Methods - Seventy patients with severe sepsis received homeopathic
treatment (n=35) or placebo (n=35). Five globules in a potency of 200c
were given at 12 h interval during the stay at the intensive care
unit. Survival after a 30 and 180 days was recorded.
Results - Three patients (2 homeopathy, 1 placebo) were excluded from
the analyses because of incomplete data. All these patients survived.
Baseline characteristics including age, sex, BMI, prior conditions,
APACHE II score, signs of sepsis, number of organ failures, need for
mechanical ventilation, need for vasopressors or veno-venous
hemofiltration, and laboratory parameters were not significantly
different between groups. On day 30, there was non-statistically
significantly trend of survival in favour of homeopathy (verum 81.8%,
placebo 67.7%, P=0.19). On day 180, survival was statistically
significantly higher with verum homeopathy (75.8% vs 50.0%, P=0.043).
No adverse effects were observed.
Conclusions - Our data suggest that homeopathic treatment may be an
useful additional therapeutic measure with a long-term benefit for
severely septic patients admitted to the intensive care unit. A
constraint to wider application of this method is the limited number
of trained homeopaths.
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