[Omeo33] Art 1189 - Homeopathy, 2011, 100 (1), 95-100

Gino Santini g.santini a ismo.it
Dom 3 Apr 2011 23:56:08 CEST


Adjunctive homeopathic treatment in patients with severe sepsis: a  
randomized, double-blind, placebo-controlled trial in an intensive  
care unit
M. Frass, M. Linkesch, S. Banyai, G. Resch, C. Dielacher, T. Löbl, C.  
Endler, M. Haidvogl, I. Muchitsch and E. Schuster

Background - Mortality in patients with severe sepsis remains high  
despite the development of several therapeutic strategies. The aim of  
this randomized, double-blind, placebo-controlled trial was to  
evaluate whether homeopathy is able to influence long-term outcome in  
critically ill patients suffering from severe sepsis.
Methods - Seventy patients with severe sepsis received homeopathic  
treatment (n=35) or placebo (n=35). Five globules in a potency of 200c  
were given at 12 h interval during the stay at the intensive care  
unit. Survival after a 30 and 180 days was recorded.
Results - Three patients (2 homeopathy, 1 placebo) were excluded from  
the analyses because of incomplete data. All these patients survived.  
Baseline characteristics including age, sex, BMI, prior conditions,  
APACHE II score, signs of sepsis, number of organ failures, need for  
mechanical ventilation, need for vasopressors or veno-venous  
hemofiltration, and laboratory parameters were not significantly  
different between groups. On day 30, there was non-statistically  
significantly trend of survival in favour of homeopathy (verum 81.8%,  
placebo 67.7%, P=0.19). On day 180, survival was statistically  
significantly higher with verum homeopathy (75.8% vs 50.0%, P=0.043).  
No adverse effects were observed.
Conclusions - Our data suggest that homeopathic treatment may be an  
useful additional therapeutic measure with a long-term benefit for  
severely septic patients admitted to the intensive care unit. A  
constraint to wider application of this method is the limited number  
of trained homeopaths.


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