[Omeo33] Art 1156 - Homeopathy, 2010, 99 (4), 249-254

[Gino Santini]

Homeopathic Symphytum officinale increases removal torque and  
radiographic bone density around titanium implants in rats
Rubens Spin-Neto, Marina Montosa Belluci, Celso Eduardo Sakakura,  
Gulnara Scaf, Maria Teresa Pepato and Elcio Marcantonio Jr.

Introduction - This study evaluated the effect of Symphytum officinale  
in homeopathic potency (6cH), on the removal torque and radiographic  
bone density around titanium implants, inserted in rats tibiae.
Methods - Implants were placed in male rat tibiae, and the animals  
randomized to two groups (Control and S. officinale 6cH treated),  
which were evaluated at 7, 14, 28 and 56 days post-implantation.  
Radiographic bone density was measured at 6 points around the implant,  
using digital radiographic images, when implants were inserted and at  
sacrifice. Removal torque of the implants was also evaluated.
Results - Both removal torque and radiographic bone density evaluation  
showed that S. officinale 6cH treatment enhanced bone formation around  
the micro-implants, mainly at 14 days. At 56 days, the radiographic  
bone density was higher in the treated group.
Conclusions - We conclude that S. officinale 6cH enhances, principally  
at the early stages of osseointegration, bone formation around  
titanium implants in rats’ tibiae, based on radiographic and  
mechanical analysis.

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