[Omeo33] Art 1112 - JACM, 2010, 16 (2), 165-173

[Gino Santini]

Complementary and Alternative Medicine Use and Quality of Life in  
Pediatric Diabetes
Rachelle L. McCarty, Wendy J. Weber, Beth Loots, Cora Collette  
Breuner, Ann Vander Stoep, Lisa Manhart, Catherine Pihoke

Objectives: The objectives of this study were to explore the  
association between complementary and alternative medicine (CAM) use  
as reported by youth, and parents' and children's reported quality of  
life in youth with diabetes.
Design: The study design was a cross-sectional survey.
Setting: Youth in Washington State participated in the SEARCH for  
Diabetes in Youth study, a national, multisite epidemiological study  
designed to assess the prevalence and incidence of diabetes in U.S.  
youth. Surveys assessing CAM utilization were mailed in January and  
April 2006.
Participants: One thousand four hundred and thirty-nine (1439) youth  
were mailed a CAM survey. The final sample consisted of 467 youth with  
both CAM survey results and quality-of-life data.
Outcome measures: Difference in mean scores on Pediatric Quality of  
Life Inventory (PedsQL) between CAM users and nonusers overall, and  
specific CAM therapies were the outcome measures.
Results: Of the 1439 participants approached, 587 (40.8%) returned the  
CAM survey. In adjusted analyses, children reported any CAM use as  
associated with more barriers to treatment (difference in mean scores  
−3.48, 95% confidence interval [CI] −6.65, −0.31). Children  
following a CAM diet reported higher quality of life (PedsQL Core  
Total difference 4.01, 95% CI [0.10–7.91]; Core Psychosocial  
difference was 6.45, 95% CI [1.95 to 10.95]), but those using stress- 
reduction activities reported poorer quality of life (Diabetes Total  
difference −4.19, 95% CI [−8.35 to −0.04]). Parent-reported  
quality of life was lower for children who used “other  
supplements” (Core Total difference −6.26, 95% CI [−11.29 to  
−1.24]; Core Psychosocial difference was −5.92, 95% CI [−11.65 to  
−0.19]).
Conclusions: CAM diets were associated with increased quality of life  
in youth with diabetes, whereas supplement use and stress-reduction  
activities were associated with decreased quality of life. The  
temporal sequence between CAM use and quality of life requires further  
study.

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