[Omeo33] Art 0948 - Homeopathy, 2008, 97 (3), 141-144

Gino Santini g.santini a ismo.it
Gio 23 Lug 2009 08:15:14 CEST


An animal model for the study of Chamomilla in stress and depression:  
pilot study
Sandra Augusta Gordinho Pinto, Elisabeth Bohland, Cideli de Paula  
Coelho, Maria Sílvia Furquim de Azevedo Morgulis and Leoni Villano  
Bonamin

The behavioral and hematological effects of treatment with Chamomilla  
6cH in mice subjected to experimental stress are described. Swiss mice  
were randomly divided into pairs, one animal was inoculated with  
Ehrlich's tumor, the other was treated daily with Chamomilla 6cH or  
control or received no treatment. After 7 days, the animals were  
observed in an open-field arena and blood samples taken. Mice who  
cohabitated with a sick cage-mate showed a decrease in their general  
activity, but those treated with Chamomilla 6cH were less severely  
affected (p = 0.0426). No hematological changes were observed.
In a second experiment, the forced swimming test was applied to mice  
pre-treated with Chamomilla 6cH, controls were: water, 10% ethanol or  
amitriptyline. Only the amitriptyline and ethanol treated groups  
showed significant excitatory behavior (p = 0.0020), Chamomilla 6cH  
treated animals' scores intermediate between water control and ethanol  
or amitriptyline. A decrease in the leukocyte count was observed in  
the amitriptyline and Chamomilla 6cH treated groups (p = 0.039). These  
data suggest that treatment with Chamomilla 6cH is related to the  
recovery of basal behavioral conditions in mice subjected to stressful  
conditions.

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