[Omeo33] Art 0964 - Homeopathy, 2009, 98 (1), 17-25

[Gino Santini]

Observational study of homeopathic and 
conventional therapies in patients with diabetic 
polyneuropathy
Raffaella Pomposelli, Valeria Piasere, Cristina 
Andreoni, Gavina Costini, Elena Tonini, 
Antonietta Spalluzzi, Daniela Rossi, Chiara 
Quarenghi, Maria Elisabetta Zanolin and Paolo 
Bellavite

Methods - The feasibility and outcomes of 
homeopathic therapy in a group of type-2 diabetes 
mellitus patients with diabetic neuropathy were 
studied in a prospective observational study. 
Patients were followed from baseline (T0) for 6 
months (T1) and for 12 months (T2), treatment was 
adjusted as necessary. Primary outcome was 
diabetic neuropathy symptom (DNS) score, 
secondary outcomes were clinical evolution and 
short-form-36 (SF-36)-evaluated quality of life 
(QOL).
Results - Homeopathy was used in 45 patients, 32 
of whom completed the observation study, and in 
parallel the conventional therapy outcomes were 
observed in 32 patients, 29 of whom completed the 
study. DNS improved in both groups during the 
observation period, but the change with respect 
to baseline was statistically significant only in 
Homeopathic group at T1 (P = 0.016). Over the 
course of the observation there was a substantial 
stability of the electroneurophysiological 
values, blood pressure and body weight in both 
groups, a slight decrease of fasting blood 
glucose and glycated haemoglobin in Homeopathic 
group. QOL scores showed an improvement in 
Homeopathic group only. The cost of conventional 
drugs decreased in Homeopathic group from 114 
¤/month to 94 ¤/month at T1.
Conclusion - Complementary homeopathic therapy of 
diabetic neuropathy was feasible and promising 
effects in symptom scores and cost savings were 
observed.

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