[Omeo33] Art 0410 - Homeopathy, 2003, 92 (3), 131-134

[Gino Santini]

The homeopathic approach to the treatment of symptoms of oestrogen  
withdrawal in breast cancer patients. A prospective observational study
E. A. Thompson and D. Reilly

This paper reports on an investigation of the homeopathic approach to  
the management of symptoms of oestrogen withdrawal in women with  
breast cancer. Forty-five patients entered the study. The most common  
presenting symptoms were hot flushes (HF) (n = 38), mood disturbance  
(n = 23), joint pain (n = 12), and fatigue (n = 16). Other symptoms  
included sleeplessness, reduced libido, weight gain, cystitis, vaginal  
dryness and skin eruptions. The active intervention was an  
individualised homeopathic medicine. Forty women (89%) completed the  
study. Significant improvements in mean symptom scores were seen over  
the study period and for the primary end-point ‘the effect on daily  
living’ scores. Symptoms other than HF such as fatigue and mood  
disturbance appear to be helped. Significant improvements in anxiety,  
depression and quality of life were demonstrated over the study  
period. The homeopathic approach appears to be clinically useful in  
the management of oestrogen withdrawal symptoms in women with breast  
cancer whether on or off Tamoxifen and improves mood disturbance. A  
placebo-controlled trial would be the next stage in this line of  
inquiry.

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