[Omeo33] Art 1032 - Homeopathy, 2009, 98 (3), 154-159

[Gino Santini]

Immunomodulatory activity of Toxicodendron pubescens in experimental  
models
C.R. Patil, P.S. Salunkhe, M.H. Gaushal, A.R. Gadekar, A.M. Agrawal  
and S.J. Surana

Background - Toxicodendron pubescens is a botanical name of Rhus  
toxicodendron (Rhus tox). This plant is widely used in its  
homeopathically diluted form in the treatment of inflammatory and  
edematous conditions. In this study, various dilutions of Rhus tox  
including its crude form have been evaluated for their effects on  
immune response in the in vivo and in vitro experimental models.
Methods - Rhus tox in the form of mother tincture, 6cH, 30cH, 200cH  
and 1000cH dilutions was tested through in vivo models including sheep  
red blood cells (SRBCs) induced cellular and humoral immune response  
in C57/BL6 mice.The effects of Rhus tox dilutions were also evaluated  
in vitro on the functions of human polymorphonuclear (PMN) cells such  
as phagocytosis and intracellular killing of Candida albicans,  
chemotaxis, and reduction of nitroblue tetrazolium (NBT) dye.
Results - Rhus tox was found to intensify SRBCs induced antibody titer  
and delayed type hypersensitivity response in mice. Even higher  
dilutions such as 200cH and 1000cH were found to affect the immune  
response; however, the crude form, mother tincture, 6cH and 30cH  
dilutions revealed more potent effects than the 200cH and 1000cH  
dilutions. In in vitro assays, all the dilutions exerted stimulation  
of phagocytosis, candidacidal activity and chemotaxis of human PMN  
cells. The NBT dye reduction assay revealed that oxidative processes  
in the PMN cells are accelerated in the presence of Rhus tox. This  
study shows that Rhus tox possesses immunostimulatory activity in its  
crude form as well as in homeopathically diluted forms. These effects  
appeared to be concentration dependent as higher dilutions had less  
potent effects.

Disponibile il full-text su richiesta
-------------- parte successiva --------------
Un allegato HTML è stato rimosso...
URL: http://sf8.starfarm.it/pipermail/omeopatia33/attachments/20090803/2d8f3193/attachment-0001.html